Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation.
|Title||Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation.|
|Publication Type||Journal Article|
|Year of Publication||2019|
|Authors||Liu G, Patch A, Bahar F, Yllanes D, Welch RD, M Marchetti C, Thutupalli S, Shaevitz JW|
|Journal||Phys Rev Lett|
|Date Published||2019 Jun 21|
|Keywords||Cell Movement, Myxococcus xanthus, Phase Transition|
Combining high-resolution single cell tracking experiments with numerical simulations, we show that starvation-induced fruiting body formation in Myxococcus xanthus is a phase separation driven by cells that tune their motility over time. The phase separation can be understood in terms of cell density and a dimensionless Péclet number that captures cell motility through speed and reversal frequency. Our work suggests that M. xanthus takes advantage of a self-driven nonequilibrium phase transition that can be controlled at the single cell level.
|Alternate Journal||Phys. Rev. Lett.|