A curious guy learning to pragmatically fit enthusiasm into space and time.

The cell comprises of several structural and functional compartments, called as organelles. These organelles co-ordinate and interact with each other to execute functional outcomes of the cell. Amongst various factors regulating these coordination, I am asking if the position and spatial organisation of organelles have a role?  In other words, is there a probabilistic distribution of organelles in the cellular space? This becomes important in the context of host-pathogen interaction because several cellular  processes during pathogen infection are an outcome of coordinated interaction of various organelles like endosomes, autophagosomes and lysosomes. Hence, studying regulatory mechanisms of their spatial organization during pathogen infection becomes fundamental to develop host-directed therapeutic strategies.