Dr Yamuna Krishnan - Publications
Publications :
- Chakraborty, S., Mehtab, S. and Krishnan, Y.* (2014) The predictive power of synthetic nucleic acid technologies in RNA biology. Acc. Chem. Res. 47, 1710-1719.
- Sharma, S., Zaveri, A., Visweswariah, S.S and Krishnan, Y.* (2014) A fluorescent nucleic acid-based nanodevice quantitatively images elevated cAMP in membrane bound compartments. Small, in press.
- Ghosh, A. and Krishnan, Y. (2014) At a long-awaited turning point. NatureNanotechnology, 9, 491-494.
- Modi, S., Halder, S., Nizak, C. and Krishnan, Y.* (2014) Recombinant antibody mediated delivery of organelle-specific DNA pH sensors along endocytic pathways.Nanoscale, 6, 1144-1152.
- Ganesh, K.N. and Krishnan Y. (2013) Nucleic Acids - Chemistry and Applications. J. Org. Chem. 78, 12283-12287.
- Modi, S., Nizak, C., Surana, S., Halder, S. and Krishnan, Y*. (2013) Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell. Nature Nanotechnology, 8, 459-467.
- Surana, S., Bhatia, D. and Krishnan, Y.* (2013) A method to study in vivo stability of DNA nanostructures. Methods, 64, 94-100.
- Banerjee, A., Bhatia, D., Saminathan, A., Chakraborty, S., Kar, S. and Krishnan, Y.* (2013) Controlled release of encapsulated cargo from a DNA icosahedron using a chemical trigger. Angew. Chem. Int. Ed. 52, 6854-6857.
- Surana, S. and Krishnan, Y.* (2013) A method to map spatiotemporal pH changes in a multicellular living organism using a DNA nanosensor. Methods Mol. Biol. 991, 9-23.
- Bhatia, D., Chakraborty, S., Mehtab, S. and Krishnan, Y.* (2013) A method to encapsulate molecular cargo within DNA icosahedra. Methods Mol. Biol. 991, 65-80.
- Bhatia, D. and Krishnan, Y. (2013) Designer nucleic acid-based devices in nanomedicine. In Erdmann, V.A., Barcisjewski, J. (eds), DNA and RNA Nanobiotechnologies in Medicine: Diagnosis and Treatment of Diseases. (in press).
- Saha, S. and Krishnan, Y. (2012) pH sensitive DNA devices. In Fox, K.R., Brown, T (ed), DNA Conjugates and Sensors. Royal Society of Chemistry publishing, Cambridge, pp166-183.
- Krishnan, Y., Bathe, M. (2012) Designer nucleic acids to probe and program the cell.Trends in Cell Biology, 22, 624-633.
- Bhatia, D., Chakraborty, S. and Krishnan, Y.* (2012) Designer DNA give RNAi more spine. Nature Nanotechnology, 7, 344-346.
- Chakraborty, S., Mehtab, S., Patwardhan, A.R., Krishnan, Y.* (2012) Pri-miR-17-92a Transcript folds into a tertiary structure and autoregulates its processing. RNA18, 1014-1028.
- Saha, S., Chakraborty, K. and Krishnan, Y*. (2012) Tunable, colorimetric DNA based pH sensors mediated by A-motif formation. Chem. Commun. 48, 2513.
- Bhatia, D., Sharma, S. and Krishnan, Y*. (2011) Synthetic, biofunctional nucleic acid-based molecular devices. Curr Opin Biotechnol, 22, 475-484.
- Modi, S. and Krishnan, Y.* (2011) A method to map spatiotemporal pH changes insde living cells using a pH triggered DNA nanoswitch. Methods Mol. Biol. 749, 61-77.
- Surana, S., Bhat, J.M., Koushika, S.P. and Krishnan, Y.* (2011) An autonomous DNA nanomachine maps spatiotemporal pH changes in a multicellular living organism. Nature Communications, 2, 340.
- Bhatia, D., Surana, S., Chakraborty, S., Koushika, S.P. and Krishnan, Y.* (2011) A synthetic, icosahedral DNA-based host-cargo complex for functional in vivo imaging.Nature Communications, 2, 339.
- Krishnan, Y and Simmel, F. C. (2011) Nucleic Acid Based Molecular Devices. Angew. Chem. Int. Ed. 50, 3124-3156.
- Modi, S., Bhatia, D., Simmel, F. C., Krishnan, Y.* (2010) Structural DNA Nanotechnology: From bases to bricks, from structure to function. J. Phys. Chem. Lett. 1, 1999-2005.
- Saha, S., Bhatia, D., Krishnan, Y.* (2010) pH toggled DNA architectures: Reversible assembly of a 3WJ into extended 1D architectures through A-motif formation .Small, 6, 1288-1292.
- Chakraborty, S., Sharma, S., Maiti, P. K., Krishnan, Y.* (2009) The poly dA helix: A new structural motif for high-performance DNA-based molecular switches . Nucleic Acids Res. 37, 2810-2817.
- Modi, S., Swetha, M. G., Goswami, D., Gupta, G. D., Mayor, S., Krishnan, Y.* (2009) A DNA nanomachine maps spatiotemporal pH changes in living cells. Nature Nanotechnology, 4, 325-330.
- Bhatia, D., Mehtab, S., Krishnan, R., Indi, S.S., Basu, A., Krishnan, Y.*(2009)Icosahedral DNA nanocapsules via modular assembly. Angew. Chem. Int. Ed. 48, 4134-4137. (featured on journal frontispiece)
- Paul, A.; Sengupta, P.; Krishnan, Y.; Ladame, S.* (2008) Combining G-quadruplex targeting motifs on a single PNA scaffold: hybrid (3+1) PNA-DNA bimolecular quadruplex. Chem.Eur.J. 14, 8682-8689.
- Chakraborty, S.; Krishnan, Y.* (2008) Kinetic Hybrid i-motifs: Intercepting DNA with RNA to form a DNA2-RNA2 i-motif. Biochimie, 90, 1088-1095.
- Chakraborty, S.; Modi, S.; Krishnan, Y.* (2008) The RNA2-PNA2 Hybrid I-motif - A novel RNA-based building block. Chem. Commun., 70-72.
- Ghodke, H. B.; Krishnan, R.; Vignesh, K.; Kumar, G.V.P.; Narayana, C.; Krishnan, Y.* (2007) The I-tetraplex building block: Rational Design and Controlled Fabrication of robust 1D DNA Scaffol ds via non-Watson Crick self assembly. Angew. Chem. Int. Ed., 46, 2646-2649.
- Gavory, G.; Symmons, M. F.; Krishnan-Ghosh, Y.;Klenerman, D.; Balasubramanian, S.* (2006) Structural Analysis of the Catalytic Core of Human Telomerase RNA by FRETand Molecular Modeling. Biochemistry, 45, 13304-13311.
- Pitchiaya, S.; Krishnan, Y.* (2006) First Blueprint, Now Bricks: DNA as construction material on the nanoscale.Chem. Soc. Rev., 35, 1111-1121.
- Modi, S., Wani, A. H., Krishnan, Y.* (2006) The PNA-DNA hybrid I-motif - Implications for sugar-sugar contacts in i-motif tetramerization. Nucleic Acids Research, 34, 4353-4363.
-
Krishnan-Ghosh, Y.; Stephens, E.; Balasubramanian, S.*
(2005) PNA forms an I-motif. Chem. Commun. 5278-5280.
- Krishnan-Ghosh, Y.; Whitney, A. M.; Balasubramanian, S.* (2005) Dynamic covalent chemistry on self-templating PNA oligomers: Formation of a bimolecular PNA quadruplex. Chem. Commun., 3068-3070.
- Krishnan-Ghosh, Y.; Liu, D.; Balasubramanian, S.* (2004) Formation of an interlocked quadruplex dimer by d(GGGT). J. Am. Chem. Soc. 126, 11009-11016.
- Krishnan-Ghosh, Y.; Stephens, E.; Balasubramanian, S.* (2004) A PNA4quadruplex. J. Am. Chem. Soc. 126, 5944-5945.
- Krishnan-Ghosh , Y.; Balasubramanian, S.* (2003) Dynamic covalent chemistry on self-templating peptides: Formation of a disulfide-linked beta-hairpin mimic. Angew. Chem. Int. Ed. 42, 2171-2173.
- Ghosh Y. K.; Visweswariah, S. S.; Bhattacharya, S. * (2002) Advantage of the ether linkage between the positive charge and the cholesteryl skeleton in cholesterol-based amphiphiles as vectors for gene delivery. Bioconjugate Chem. 13, 378-384.
- Bhattacharya, S.*; Krishnan-Ghosh, Y. (2002) 2-Halooxyethylene ethers of cholesterol as novel single component, room temperature cholesteric LC materials.Mol. Cryst. Liq. Cryst. 381, 33-41.
- Wills, A. J.; Krishnan-Ghosh, Y.; Balasubramanian S.* (2002) Synthesis of a polymer-supported oxazolidine aldehyde for asymmetric chemistry. J. Org. Chem.67, 6646-6652.
- Horsey, I.; Krishnan-Ghosh, Y.; Balasubramanian, S. (2002) Enhanced cooperative binding of oligonucleotides to form DNA duplexes mediated by metal ion chelationChem. Commun. 1950-1951.
- Bhattacharya, S.; Krishnan-Ghosh, Y. (2001) First report of phase selective gelation of oil from oil/water mixtures. Possible implications toward containing oil spills.Chem. Commun., 185-186.
- Bhattacharya, S.; Krishnan-Ghosh, Y. (2001) Vesicle formation from oligo(oxyethylene)-bearing cholesteryl amphiphiles: Site-selective effects of oxyethylene units on the membrane order and thickness. Langmuir 17, 2067-2075.
- Krishnan-Ghosh, Y.; Gopalan, R. S.; Kulkarni, G. U.; Bhattacharya, S. (2001) Structure of cholest-5-en-3 beta-oxy-5-bromopentane by single-crystal X-ray diffraction at 130 K. J. Mol. Structure 560, 345-355.
- Krishnan-Ghosh, Y.; Bhattacharya, S.* (2001) Membrane formation from oxyethylene bearing cationic cholesterol derivatives. Ind. J. Chem. B. 40, 891-894.
- Krishnan-Ghosh, Y., Bhattacharya, S.* (2001) Thermal lipid order-disorder transitions in mixtures of cationic cholesteryl lipid analogues and dipalmitoyl phosphatidylcholine membranes. J. Phys. Chem. B. 105, 10257-10265.
- Ghosh, Y.K., Visweswariah, S. S., Bhattacharya, S.* (2000) Nature of linkage between cationic headgroup and cholesteryl skeleton controls gene transfection efficiency . FEBS Lett. 473, 341-344