Pathways of clathrin-independent endocytosis.
Title | Pathways of clathrin-independent endocytosis. |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Mayor S, Pagano RE |
Journal | Nat Rev Mol Cell Biol |
Volume | 8 |
Issue | 8 |
Pagination | 603-12 |
Date Published | 2007 Aug |
ISSN | 1471-0072 |
Keywords | Animals, Bacteria, Biological Transport, Active, Clathrin, Endocytosis, Eukaryotic Cells, Humans, Virus Internalization, Viruses |
Abstract | There are numerous ways that endocytic cargo molecules may be internalized from the surface of eukaryotic cells. In addition to the classical clathrin-dependent mechanism of endocytosis, several pathways that do not use a clathrin coat are emerging. These pathways transport a diverse array of cargoes and are sometimes hijacked by bacteria and viruses to gain access to the host cell. Here, we review our current understanding of various clathrin-independent mechanisms of endocytosis and propose a classification scheme to help organize the data in this complex and evolving field. |
DOI | 10.1038/nrm2216 |
Alternate Journal | Nat. Rev. Mol. Cell Biol. |
PubMed ID | 17609668 |
Grant List | / / Wellcome Trust / United Kingdom |